CURRICULUM VITAE
Personal
Information
Full name: Mehmet Sefa Ulutaş
Date of birth: 1988
Place of birth: Samsun, Turkey
Address: Department of Biology, Faculty of Art and
Science, Siirt University, 56100 Siirt, Turkey
Phone: +90 5059890404
Email: sefa.ulutas@siirt.edu.tr / sefaulutas@gmail.com
Education
2014 - 2021 Ph.D. in Biotechnology
Middle East
Technical University, Graduate School of Natural and Applied Sciences. Ankara,
Turkey.
Subject: Interaction of Intestinal
Microbiota and Intestinal Epithelial Health in High Carbohydrate Diet
2011
- 2013 M.Sc.
in Molecular Biology and Genetic & Biotechnology
Istanbul Technical
University, Graduate School. Istanbul, Turkey
Subject: Characterization
of Microbial Community in Lab-Scale Enhanced Biological Phosphorus Removal
Reactors with Fluorescence in Situ Hybridization
2006 - 2011 B.Sc. in Molecular Biology
and Genetic
Istanbul Technical
University, Faculty of Science and Letter, Istanbul, Turkey.
Employment and Experience
2023 - Present Assistant
Professor
Department
of Biology, Faculty of Arts and Sciences, Siirt University,
Siirt, Turkey.
2020 - 2022 Research Assistant
Department of
Biology, Faculty of Arts and Sciences, Siirt University,
Siirt, Turkey.
2019 - 2020 Doctoral
Fellow (Visiting Researcher)
Massachusetts
Institute of Technology (MIT) Koch Institute Integrative Cancer Research
Center. Massachusetts, MA, United State.
2014 - 2019 Research Assistant
Middle East
Technical University, Graduate School of Natural and Applied Sciences. Ankara,
Turkey.
2011 - 2013 Research Assistant
Istanbul Technical
University, Faculty of Science and Letter, Istanbul, Turkey.
Publications
International Peer-Review Journal Papers
1.
Ulutas M.S., Cebeci A. A. (2023). High Carbohydrate
Diet Decreases Microbial Diversity and Increases IL-1β Levels in Mice Colon. Turkish
Journal of Biology (Under Review)
2.
Ulutas M.S., Cebeci A. A. (2023). Macronutrients in Diets Differentially Affect
Gastrointestinal Cytokine and Tight Junction Protein Levels. Brazilian Journal
of Nutritions. (Under Review)
3. Fincan, S.
A., Özdemir, S., Karakaya, A., Enez, B., Mustafov, S. D., Ulutaş M. S.,
& Şen, F. (2021). “Purification and characterization of thermostable
α-amylase produced from Bacillus licheniformis So-B3 and its potential in
hydrolyzing raw starch. Life sciences, 264, 118639.
4.
Cheng C.W., Biton M, Haber A.L., Ulutas M.S, et al. (2019)
Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation
to Diet. Cell. 2019;178(5):1115-1131.e15.
doi:10.1016/j.cell.2019.07.048
5.
Özdemir
S., Okumuş, V., Ulutaş M. S., Dündar
A., Akarsubaşı A. T., Dumonted S., (2016) Production and characterization of
thermostable α-amylase from thermophilic Anoxybacillus
flavithermus sp. nov. SO-19, Starch, 68: 1244-1253
6.
Özdemir
S., Okumuş, V., Ulutaş M. S., Dündar
A., Akarsubaşı A. T., Dumonted S. (2015) Isolation of a Novel Thermophilic
Anoxybacillus flavithermus SO- 13, Production, Characterization and Industrial
Applications of its Thermostable α-Amylase, Journal of Bioprocessing &
Biotechniques, 5:3-9.
7. Bermek H, Catal T, Akan S.S, Ulutaş
M.S, Kumru M, Özgüven M, Liu H, Özçelik B, Akarsubaşı A.T (2014) Olive mill
wastewater treatment in single-chamber air-cathode microbial fuel cells, World J Microbiol Biotechnol. 1177-85.
8.
Özdemir
S., Matpan F., Okumuş, V., Dündar A., Ulutaş
M. S., Kumru M., (2012), Isolation of a thermophilic Anocybacillus flavithermus
sp. Nov. and production of thermostable α-amylase under solid-state
fermentation (SSF), Ann Microbiol 62: 1367-1375.
International Conference Proceedings Publications
1. Cebeci A.
A, Ulutas M.S., (2021).
Effects of high carbohydrate diet on intestinal microbiota and
inflammatory markers. EMBO | EMBL Symposium: New Approaches and Concepts in
Microbiology
2. Cheng C.W., Kocal G.C., Ulutas M. S., Iqbal M., Yilmaz O. H. (2019) Divergent roles of
Hmgcs2 in intestinal regeneration and colon tumor development. Koch Institute
Annual Retreat, November 14 2019, Massachusetts/USA
3. Ulutas
M.S., Gürakan G.C., Cebeci A.,
Aydın E., Dogan O., (2018) Intestinal
Microbial Diversity Changes Significantly on a Western Diet, 6th
World Congress on Targeting Microbiota, October 28-30 2018 Porto/Portugal
4. S. Ozdemir, V. Okumus, A. Dundar, M.S. Ulutas, A.T. Akarsubasi, (2014), ''Newly Isolated
thermophilic Anoxybacillus flavithermus SO-10, its α-amylase production,
characterization and usage in fruit juice industry'' 3rd International Molecular
Biology and Biotechnology Congress, Sarajevo/ bosnia herzogevina, June 2-6 July 2014, Page:29
5. V. Okumus, S.
Ozdemir, M.S. Ulutas, A. Dundar, A.T. Akarsubasi, (2014), ''Isolation
of Thermophilic Geobacillus stearothermophilus and its α-amylase
production and characterisation'' 3rd International Molecular Biology and Biotechnology
Congress, Sarajevo/ Bosnia Herzogevina, June 2-6 July 2014, Page:38
6. Ulutaş
M. S., Tatlı M., Akan S., Kumru
M., Kurt H., Bermek H., Akarsubaşı A. T., (2012). Characterization and
Evolution of Microbial Communities In Olive Mill Wastewater Degrading Microbial
Fuel Cells, International
Society for Microbial Ecology Conference, 19-24 Agust 2012, Copenhagen/Denmark.
7. Ulutaş
M.S., Kumru M., Kurt H., Bermek
H., Akarsubaşı A. T., (2011), Characterization of Microbial Communities In
Olive Oil Wastewater Degrading, Microbial Fuel Cells, International Conference on Enzyme Science and
Technology (ICEST2011) October 31- November 4, 2011. Kusadası/Aydın/Turkey.
National Conference Proceedings Publications
1.
A.
Dündar, M.S. Ulutaş, S. Özdemir, V.
Okumuş, (2015), Production and
characterization of thermostable α-Amylase from thermophilic Anoxybacillus
flavithermus sp nov. 18th
Biotechnology Congress, December 18-19, 2015. Konya/Turkey.
2.
V. Okumus, S. Ozdemir, A. Dundar, M.S. Ulutas, Protease
production from thermophilic Bacillus pumilus by using lentil husks with solid
state fermentation (SSF) technique, Ecology 2015 symposium, 06-09 May 2015.
Sinop University, Sinop/Turkey.
3.
S. Ozdemir, V. Okumus, M.S. Ulutas, A. Dundar. α-amilaseproduction from thermophilic anoxybacillus
kestanbolensis SO-18 strain by using agricultural waste with solid state
fermentation (SSF) technique, Ecology 2015 symposium, 06-09 May 2015. Sinop
University, Sinop/Turkey.
4.
Ulutaş M.S., Şahin, U., Optimization of
production TaqI endonuclease enzyme
within Recombinant Escherichia coli
by Fuzzy inference systems -BMYS2010- 4th Symposium on Modern Methods in
Science. 14-16 October, 2010, Dicle University, Diyarbakir/Turkey.
5.
Öztürk M,
Hançer M., Ulutaş M. S., Can M.,
Tartik M., Günel A., Şahin, U., Duran, A. Ş., Akyüz, D. E., A new approach
loss-saving energy at buildings wall based on fuzzy logic calculation BMYS2010-
4th Symposium on Modern Methods in Science. 14-16 October, 2010, Dicle
University, Diyarbakir/Turkey.
Projects
1.
Cebeci A.
A., Yilmaz O. H., Ulutaş M.S.
(2021). Understanding the role of intestinal ketone bodies on
the microbiome. MISTI (Massachusetts
Institute of Technology (MIT) International Science &
Technology Initiatives)
2.
Cebeci
A.A., Ulutaş M.S., (Ongoıng) Investigation of intestinal microbiota and its interaction
with intestinal stem cells, BAP, Abdullah Gül University.
3.
Aydın E., (Project Executive) Ulutas M. S., (2018) Development of
Kidney Targeted siRNA Carrier Nanoparticle Formulation for Chemo-protection of
Cisplatin Nephrotoxicity, TÜBİTAK Project, 117S449
4.
Gültekin
G. C., (Project
Executive), Ulutaş M.S. (2017) Characterization
genotypic differences of Lactobacillus
delbrueckii subsp. Bulgaricus cultures isolated from traditional Turkish
yogurt by 16S rDNA sequencing and PFGE method. BAP-03-14-2017-004, Middle East Technical University.
Awards
Doctoral Fellowship of the Scientific and
Technological Research Council of Turkey, TÜBİTAK 2214a (App No: 1059B141800345).
Subject: Effects of High Fat and Calorie restricted
diets on the intestinal microbiota and epithelial health. Place: Massachusetts
Institute of Technology (MIT), Massachusetts, at the Koch Institute Integrative
Cancer Research Center,
Massachusetts/USA. 2019-2020 (one year).
Skills
·
Molecular biology techniques: DNA
extraction, RNA extraction, Protein extraction. PCR, RT-PCR, Western Blotting.
In situ Hybridization, Immunohistochemical Assay.
·
Microbiology techniques: Media
preparation, sterilization, culturing, counting
·
Cell culture techniques: Expreinced in
cell culture specifically organoid culture techniques and imaging systems.
·
Experienced in housing mouse, mating mouse
and genetically modified mouse.
·
Experienced in the study of microbe-host
immune interactions, microbiome-gut health interaction and gut microbiota
analysis.
· Experienced in DNA extraction, library preparation, and 16S/shotgun
sequence analysis.